TG and thyroid cancer: This finding is in line with a previous retrospective review by Sands et al. [22] in which 68 patients who underwent thyroidectomy for a nodule with an indeterminate cytology (Bethesda III-V), mean preoperative thyroglobulin levels were significantly higher in patients with well-differentiated thyroid cancer (223 mcg/L) compared to those with a benign pathology (53 mcg/L), suggesting that preoperative thyroglobulin is a useful aid when making management decisions in patients with indeterminate cytology.