GSN and cancer: In analogy to antimicrobial and anti-cancer nanoformulations, aminosilane- (MNP@NH2) and gold-coated magnetic nanoparticles (MNP@Au) were also noted to exert anti-inflammatory effects in LPS/LTA-stimulated keratinocytes and augment the beneficial effects of PBP10 peptides, which are derived from human plasma gelsolin (pGSN) and are structurally and functionally similar to AMPs (cationic charge, a short sequence, membrane-permeabilizing properties and amphipathic chemical character and resulted from this, broad spectrum of antimicrobial activity) [158].