ADSL and cancer: Other cellular physiology-associated factors enhancing the selectivity of AMPs for cancer cells and facilitating killing are: (i) enhanced fluidity of cancerous cell membranes associated with incorporation of lower levels of cholesterol in transformed cells [107–109] (there are, however, conflicting reports [110, 111]) and (ii) increased surface area with enhanced number of microvilli, which facilitate the binding of AMPs and disruption of cell membranes [112].