Additionally, our finding that fisetin and quercetin treatments reduce phosphorylation of mutant p53 to interfere with TNBC cell migration is consistent with the role of gain-of-function mutant p53 in tumorigenesis, migration, invasion, and metastasis of cancer cells, through various mechanisms such as binding to and inactivating p63 and the Mre11 nuclease [42–44]. The gene discussed is TP53; the disease is cancer.