As to the comparative studies to assess the amounts of GAGs and disaccharides in the CM derived from H1299/Mock versus H1299/SRGN cells and H460/sh-CTRL versus H460/sh-SRGN cells, the differential amounts associated with SRGN expression in these two NSCLC cells may be indicative of the relative amounts of GAGs and disaccharides associated with SRGN, but may also contain the components derived from other proteoglycans whose expression is regulated by SRGN expression. Here, SRGN is linked to non-small cell lung carcinoma.