It has been proven that overexpression of ILK was crucial for carcinogenesis and metastasis in assorted cancer types, including colorectal cancer 8, renal cell carcinoma 11, thyroid cancer 12, breast cancer 6, 13, non-small cell lung cancer 17, 18, prostate cancer 19, 20. The gene discussed is ILK; the disease is hereditary clear cell renal cell carcinoma.