The univariate analyses demonstrated a significant association between the presence of BRAF-V600E and tumor size (P<0.001), multifocality (P=0.036), histology (P<0.001), RAI dose (P<0.001), follow-up time (P=0.001) and recurrence risk stage (P<0.001), whereas there was no significant association with age, sex, ethnicity, lymphocytic thyroiditis, lymph node positivity, ETE, residual tumor, RAI treatment, recurrence, TNM stage and AJCC stage (Table I). Here, BRAF is linked to Hashimoto thyroiditis.