In the ≥55 years age group, the results on univariate analysis demonstrated a significant association between BRAF-V600E mutation and tumor size (P=0.036), histology (P<0.001), RAI therapy dose (P=0.032), recurrence follow-up time (P=0.018), recurrence (P=0.031), mortality follow-up time (P=0.006), recurrence risk stage (P<0.001), advanced T stage (P=0.036), advanced N stage (P=0.036) and advanced AJCC stage (P=0.016) (Table II). Here, BRAF is linked to neoplasm.