CD93 and chronic myelogenous leukemia, BCR-ABL1 positive: Here, we demonstrate consistent and selective expression of CD93 on a lin−CD34+CD38−CD90+ CP-CML LSC population and show robust engraftment of this population in patient-derived xenograft (PDX) models in comparison with CD93− CML stem/progenitor cells, which fail to engraft, confirming its relevance in CP-CML.