These DEGs were shown to be mostly involved in cell adhesion, angiogenesis and cell proliferation for the GO BP term analysis and conformed our knowledge that these factors were of vital importance for tumor development and progression.[24–28] Moreover, the DEGs were found significantly enriched in KEEG pathways of PPAR signaling pathway, pathways in cancer, focal adhesion and AMPK signaling pathway. This evidence concerns the gene PPARA and cancer.