Besides, epithelial‐mesenchymal transition (EMT) has been associated with acquired resistance to EGFR‐TKIs, with a decrease in epithelial markers such as E‐cadherin and an increase in mesenchymal markers such as vimentin.30 Richard et al31 also found that mesenchymal NSCLC‐derived exosomes from chemoresistant cells are capable of transferring resistance to chemosensitive epithelial cells. The gene discussed is CDH1; the disease is non-small cell lung carcinoma.