PTEN deletions are linked to poor prognosis in PCa.27 Many prognostic features fail to further stratify patient outcome in molecular subgroups that are already defined by PTEN deletion.43 The significant link between low‐level survivin staining and tumor proliferation would be consistent with a role of survivin expression in the control of cellular proliferation as suggested by several authors.35, 44 That association between survivin expression levels and Ki‐67 LI were not found in Gleason score 4 + 3 and ≥4 + 4 tumors might be caused by low case numbers in these particular groups. This evidence concerns the gene PTEN and neoplasm.