FLT3 and acute myeloid leukemia: The result showed that except for OS, the MPG6 score was significantly associated with other clinical indicators such as WBC count (Wilcoxon rank-sum test p = 0.0053), EFS month (log rank test p = 0.0071 in TCGA CN-AML cohort and p <0.0001 in GSE6891 cohort) (Fig. 1c) and the presence of FLT3-ITD mutation (Fisher's exact test p = 0.0248) (Table 3).