Our data suggest that there is a significant difference between the sites of lymphoma hence suggest that lymphoma sites played an important role for gene abnormalities for BCL2, C-MYC and IgH. In support with other previous studies, BCL6 remained the highest gene aberrations for B-cell NHL and BCL2/BCL6 gene aberrations frequently occurred compared to other gene aberrations combinations. The gene discussed is BCL2; the disease is lymphoma.