The analysis conducted on ANGPT2 was parallel to VEGFA, namely higher mRNA level of ANGPT2 predicted poor OS (HR=1.28, 95% CI: 1.01-1.63, P=0.038) (Figure 6G) and PFS (HR=1.3, 95% CI: 1.02-1.9, P=0.038) (Figure 6H) in ADC patients. The gene discussed is ANGPT2; the disease is AIDS dementia complex.