As the data extracted were not sufficient to conduct pooled analysis for histological grade, GSE68465 including 443 ADC was interrogated to evaluate the mRNA levels of VEGFA in different grades, which showed that ADC patients with high grade expressed more VEGFA than patients with low grade (P<0.0001 and P=0.0009) (Figure 3G). The gene discussed is VEGFA; the disease is AIDS dementia complex.