The meta-analyses suggested that the correlation between ANGPT2 mRNA expression and TNM stage of ADC hovered around significance (OR=1.44, 95% CI: 0.96-2.14, P=0.415, and I2=1.3%) (Figure 4E) and there was no statistical difference of the ANGPT2 mRNA between the big tumor size (T3-T4) and small tumor size (T1-T2) (OR=1.17, 95% CI: 0.74-1.86, P=0.226, and I2=27.8%) (Figure 4G) in ADC. Here, ANGPT2 is linked to neoplasm.