KEGG functional enrichment analysis suggested that DEGs in AITL samples were mainly enriched in the ECM-receptor interaction, cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, NF- κB signaling pathway, cell cycle, apoptosis, and TNF signaling pathway (Fig. 1D). The gene discussed is AKT1; the disease is angioimmunoblastic T-cell lymphoma.