Based on GO enrichment analysis, we suggested some key DEGs are enriched in inflammatory response (IL18, TNF/TNFRSF, TLR9, CXCL10, S1PR3, NLRC4, MYD88), cell chemotaxis (CCL-2, -8, -5, 18, 19, 21, CXCL-9, -10, -12, -14, CXCR-2, -3, -6), cell migration (PDGFRA, JAMA, PTPN6, CD274), and angiogenesis (VEGF, IL18, CXCR3, TGFβ1, ACVRL1, COL15A1) in AITL. This evidence concerns the gene S1PR3 and angioimmunoblastic T-cell lymphoma.