However, we found 14 patients with PD-1 low expression, and further found that these patients had CXCL13, CD10, BCL-6 and other Tfh-related antigen expression, meanwhile, combined with pathomorphological features to confirm the diagnosis of AITL, which was consistent with previous reports 20,21. The gene discussed is CXCL13; the disease is angioimmunoblastic T-cell lymphoma.