A recent report from Malaysia indicates that in addition to not using ART and a CD4 ≤ 200 (aHR: 3.89, 95%CI: 1.20 – 12.63), having three or more opportunistic infections (aHR: 3.61, 95%CI: 1.04 – 12.53) are risk factors for mortality in TB/HIV co-infected individuals (21). The gene discussed is CD4; the disease is Opportunistic infection.