IL10 and Sepsis: This study was published on Nature Medicine in 2009, whose corresponding author was Mezey E. They found that co-culture of macrophages with bone marrow stromal cells could induce release of interleukin-10 through prostaglandin E2 and prostaglandin EP2/EP4 receptors dependent manners, thereby it might serve as a potential therapeutic target in the treatment of sepsis 33.