APAF1 and chronic myelogenous leukemia, BCR-ABL1 positive: Zheng et al. (2016) examined the associations of SNPs in apoptotic pathway genes including APAF1 with chronic myeloid leukemia; they reported no significant results for the impact of rs1439123 and rs2288713 on the APAF1 gene (Zheng et al., 2016).