To study how BLMH expression is affected by the chronic inflammatory environment in AD, we used the DiseaseLand transcriptomic database to perform a meta-analysis of 7 AD cohorts (Table 1) and discovered a reduction of BLMH gene expression correlated with increased CXCL8 and GROα in skin from AD patients compared to healthy individuals in the majority of the clinical studies (Fig. 1A). The gene discussed is CXCL8; the disease is Alzheimer disease.