CJD patients linked to the V2 strain (26 VV2 and 20 MV2K) showed significantly higher CHIT1 levels than those related to the M1 strain [34 MM(V)1] (p = 0.048; p = 0.025 after the exclusion of the homozygotes for the 24-bp duplication) (Fig. 2a, b). The gene discussed is CHIT1; the disease is Creutzfeldt Jacob disease.