In our study, calcifications were detected in 50% of Xp11.2/TFE3 RCC cases and were more common in Xp11.2/TFE3 RCC than in ccRCC or pRCC; the calcifications appeared in a circular arrangement around or within the tumour (Fig. 1), which was in agreement with the findings of a previous report [21]. The gene discussed is TFE3; the disease is neoplasm.