Previous studies reported that the presence of a pseudocapsule was a pathologic feature often observed in the early stage of RCCs or in low-grade RCCs [28], the incidence of pseudocapsule in Xp11.2/TFE3 RCC reached 63.6% [29], while in our study, a pseudocapsule was present in only 6 cases (33.3%). The gene discussed is TFE3; the disease is renal cell carcinoma.