IGF1 and neoplasm: In contrast, the expression of GGI-GS, DiLeoRBloss-GS, Rbloss-GS, CIN70-GS, E2FmotifCellCycleAssociated-GS, Gene70-GS, E2F4activation-GS, AURKA-GS, PTEN-GS, E2Factivation-GS, and IGF1-GS were significantly higher in the noCCCA tumours (all p < 0.0001) (Table 2; Additional file 2: Table S7).