In contrast, albumin leakage to the effluent by MCO HD (median 3.16 g session− 1, interquartile range 2.17–3.59 g session− 1) was greater, compared to both HF HD (median 0.06 g session− 1, interquartile range 0.03–0.13 g session− 1) and predilution OL-HDF (median 0.07 g session− 1, interquartile range 0.05–0.74 g session− 1), (P = 0.009) (Table 4). This evidence concerns the gene ALB and hydrops fetalis.