TLE1 and Alzheimer disease: In a study aimed to identify the therapeutic effect of GRg1 and AGR in the animal model of AD, Shi et al. [55] found that the combination of GRg1 and AGR promoted the expression of miR-873-5p, suggesting that these non-traditional drugs might have some benefit in the AD treatment with a potential mechanism in part mediated by miR-873-5p.