Cardiac transcript levels for collagen-I (Figure 2f) and collagen-III (Figure 2g) were not statistically different between the corin-Tg(i), DCM and corin-WT/DCM groups at 90 days of age, although their levels in both groups were significantly elevated above levels observed in WT mice of similar ages. Here, CORIN is linked to familial dilated cardiomyopathy.