The aim of this study was to comparatively assess the levels of NSE and CEA using three different methods of analysis: (1) ELISA kit (the accredited method of analysis), (2) the stochastic method (developed earlier by Stefan-van Staden), and (3) IHC-for tissue samples, in order to be able to implement after clinical studies the stochastic method as a very fast, reliable and cheap method of whole blood screening in order to: (1) facilitate early detection of microcellular lung cancer, and (2) facilitate the evaluation of the efficiency of treatment of patients with microcellular lung cancer. The gene discussed is ENO2; the disease is lung carcinoma.