In general, both inflammatory cytokines such as type I and type II interferons (IFNs), interleukin-6 (IL-6), IL-1, tumor necrosis factor-alpha (TNF-α), and immunoregulatory cytokines including IL-10 and transforming growth factor-beta (TGF-β) contribute to the cytokine dysregulated state in SLE [3,4]. Here, SGCG is linked to systemic lupus erythematosus.