Furthermore, bioinformatics analyses revealed the involvement of NCAPH in regulating cell division, mitotic nuclear division, G2/M and G1/S transitions of the mitotic cell cycle, and cell proliferation by interacting with NCAPD2, NCAPG, SMC2, SMC4, Aurora kinase A (AURKA), AURKB, cyclin-dependent kinase 1, H2A histone family member Z (H2AFZ), POC1 centriolar protein A (POC1A), and histone cluster 2 H2A family member C in prostate cancer [7]. Here, SMC4 is linked to Familial prostate cancer.