For example, low dose nerve agents, other acetylcholinesterase inhibitors, mild traumatic brain injury and epilepsy induce anxiety states that may be the results of long term dysfunction of γ-aminobutyric acid (GABA), cholinergic muscarinic and nicotinic receptor, and other neurotransmitter systems in the basolateral amygdala and connected brain regions [129–132]. This evidence concerns the gene ACHE and Anxiety.