To begin testing the function of EZH2 in human TLE, we compared the expression levels of M-1 genes in the above TLE samples and 55 post mortem hippocampal transcriptomes from individuals with no psychiatric or neurological disorders, substance abuse, or any first-degree relative with a psychiatric disorder as described in Li et al (GSE45642)[30]. The gene discussed is EZH2; the disease is nervous system disorder.