Consistent with this view, SG may kill Trop‐2‐positive tumor cells by intracellular intake of SN‐38, while neighboring cells (i.e., Trop‐2‐negative tumor and/or endothelial/stromal cells) may be killed by the extracellular release of SN‐38 (Goldenberg et al., 2015). The gene discussed is TACSTD2; the disease is neoplasm.