Tumors driven by H‐Ras were reported to be maintained by calcium signaling pathways.50 Wang51 established that the Wnt‐Ca2+ pathway was a key pathway that promoted the development and progression of tumors with K‐Ras mutations and proposed that blocking the combination of K‐Ras and calmodulin could be a potential treatment strategy for cancer with K‐Ras mutations. This evidence concerns the gene KRAS and cancer.