Among breast cancer patients without lymph node metastasis, patients with lower TOB1 expression had a worse prognosis.18 In patients with intestinal gastric cancer, low TOB1 and high phosphorylation of TOB1 both predicted poor prognosis.25 No studies have been conducted on the expression of TOB1 in pancreatic cancer tissues. The gene discussed is TOB1; the disease is metastatic malignant neoplasm in the lymph nodes.