TOB1 and pancreatic adenocarcinoma: After dividing TOB1 mRNA expression into high and low according to the median, we analyzed the association between TOB1 mRNA expression levels and survival time in 174 pancreatic cancer patients (four patients were excluded because of no survival data), which showed that patients with high TOB1 mRNA expression had worse outcomes than patients with low TOB1 mRNA expression (P = .002, Figure S2), but its mRNA expression level had no relationship with clinicopathological characteristics of PAAD tissues (Table S4).