NAC has been proven to inhibit the growth of lung carcinomas by reducing cell proliferation and facilitating apoptosis in tobacco carcinogen‐treated A/J mice.32 NAC exerts inhibitory effect on tumor growth via modulation of EGFR/AKT signaling and HBP1 expression in EGFR‐overexpressed oral cancer.33 It can be inferred that NAC has promising potential to be a novel anticancer agent. Here, AKT1 is linked to lip and oral cavity carcinoma.