We demonstrate here that disc degeneration induced by a needle stab‐injury rat model caused an acute inflammatory response, associated with increased levels of pro‐inflammatory cytokines, IL‐6, IL‐1β, and TNF‐α—particularly at day 7—and is consistent with previous investigations.3, 14, 15, 16, 52 Furthermore, we demonstrate that PEMF can blunt these acute inflammatory effects. This evidence concerns the gene IL1B and intervertebral disk degenerative disorder.