WNT5A and diabetic kidney disease: Wnt5a levels were clearly decreased in DKD patients compared to onset T2DM and healthy controls (50.42 ± 10.46 ng/ml versus 69.38 ± 5.68 ng/ml and 64.73 ± 8.49 ng/ml, P < 0.001) (Fig. 1a and Table 3).