Interestingly, the same research group in an independent study (with an independent panel of patients and using a different peptide quantification approach) discovered among others elevated levels of nidogen-1 (NID1) and serpin H1 (SERPINH1) along with proteins of the aminoacyl-tRNA biosynthesis pathway (IARS, KARS, WARS, and YARS) when they examined tumor interstitial fluids (TIF) in comparison with fluids from adjacent noncancerous (NIF) tissues. This evidence concerns the gene SERPINH1 and neoplasm.