Since cancer cells have been suggested to be intrinsically glycolytic, and also since we previously noted that human CD34+ cells expressing various oncogenes have been described to express hypoxic gene signatures even when cultured under normoxic conditions [41], we questioned whether at baseline under normoxic conditions the expression of glycolysis, TCA cycle or glutaminolysis-related genes would be different between normal CD34+ stem/progenitor cells and leukemic cells. Here, CD34 is linked to cancer.