CD74 and cancer: CD74 was previously shown to be decreased in cancer samples based on mRNA levels (NAP/NC ratio log2 − 0.169, CC NM/NC − 1.966 and CC M/NC − 2.601) and CEACAM-7 (NAP/NC ratio log2 − 2.054, CC NM/NC − 3.259 and CC M/NC − 3.911) based on immunohistochemistry staining.