All thirteen comparable variables (i.e., sex, age at diagnosis, primary tumor site, histological type, pathological grade, adjuvant chemotherapy, LNH, LODDS stage, tumor size, CEA level, marital status, T stage, and N stage) were defined as independent prognostic factors predicting the OS of stage I–III colon cancer patients (Table 3). This evidence concerns the gene CEACAM5 and malignant colon neoplasm.