In addition, univariate Cox regression analysis showed that preoperative blood glucose (P < 0.001), lymph node metastasis (P = 0.013), distant metastasis (P < 0.001), TNM stage (P = 0.006) and ENO1 expression (P = 0.001) were associated with OS. The gene discussed is ENO1; the disease is metastatic malignant neoplasm in the lymph nodes.