In order to further clarify the biologic function of CBX8 in metastasis of HCC cells, we detected the expression of CBX8 protein in several HCC cell lines, SK-Hep-1, Bel-7402, Hep3B, Li-7, HepG2, Huh-7 and SMMC-7721. Here, CBX8 is linked to hepatocellular carcinoma.