To the best of the authors’ knowledge, no current data is available on MHR or MLR values in patients with psoriasis, and only a few studies have investigated NLR and PLR values in psoriasis.6, 9, 10, 11, 12 Therefore, to better understand these serum inflammatory parameters in psoriasis and to evaluate the association with the disease activity, a retrospective study to assess CRP, MHR, NLR, PLR, and MLR all together in psoriasis was conducted. This evidence concerns the gene CRP and psoriasis.