TSPYL5 and neoplasm: Among these genes, six (HOXA6, STC2, HSD17B8, TFAP2A, CYP1B1, and HOXC8) were reported to be osteogenesis-/chondrogenesis-related genes, and five (ADRA1A, TSPYL5, TES, TNFRSF10D, and MBP) were reported to be tumor-suppressor genes (Fig. 3).