The other clinicopathologic factors associated with cancer-specific survival were the pathologic tumor size (p = 0.0006, HR = 1.82 if pT ≥ 20 mm), pathologic nodal stage (p = 0.0001, HR = 2.03 if pN+), distant metastasis (p = 0.0003, HR = 3.40 if M1), lymphovascular invasion (p < 0.0001, HR = 2.86 if LVI+), tumor-associated inflammation (p = 0.010, HR = 1.59 if moderate to severe), and PR positivity (p = 0.002, HR = 0.25 if PR ≥ 10%). This evidence concerns the gene PGR and cancer.