Moreover, using the same experimental population, Petry et al. [32] found that Adiponectin (ADIPOQ), Paired related Homeobox 1 (PRRX1), ABI family member 3 NESH binding protein P (ABI3B) and COL8A1 genes were also downregulated in FHS-affected group by qPCR, confirming their involvement with ECM, cell adhesion and bone formation. Here, PRRX1 is linked to Floating-Harbor syndrome.