We showed that the expression of Dlg4, Gria1, Grin2a, Gng3, Gnb5, MapK8, and Bdnf (encoding PSD-95, GluA1, GluNMDA2A, G-protein subunit gamma 3, G-protein subunit beta 5, JNK, and BDNF, respectively) was strongly reduced 1 week after stroke. The gene discussed is GNB5; the disease is stroke disorder.