At 8 weeks post-stroke, the top 10 genes were Cd44 (degree = 14), Fcgr2b (degree = 13), C1qb (degree = 13), Cd74 (degree = 12), C1qc (degree = 11), Cd14 (degree = 10), C4a (degree = 10), Spp1 (degree = 10), RT1-A2 (degree = 9), and Itgb2 (degree = 9). The gene discussed is SPP1; the disease is Stroke.