GRN and neoplasm: Multivariate Cox’s regression analysis adjusted for the Gleason score, tumor stage and age (Table 4) revealed that GP88 staining was an independent prognostic factor of OS (HR = 1.8; p = 0.011), DSS (HR = 2.4; p = 0.039) and RFS (HR = 1.7; p = 0.046), respectively.