CXCL8 and Ito hypomelanosis: The cohort study design and the collection of same-day serum samples in this study allowed the investigators to try to determine the “real-life” diagnostic potential of these cytokines for diagnosing IPA and IMI, without having to take into account numerous covariates, and to evaluate combinations of biomarkers such as IL-8 with other diagnostic tests, such as BALF PCR and BALF LFD.