For instance, there was a constitutively high level of autophagy in these apoptosis-resistant cell lines (mostly DLBCL and PTLD), which express high levels of the pro-autophagic protein, BECN1/Beclin 1, based on the activation of NF-κB signaling by LMP1 [45]. The gene discussed is BECN1; the disease is diffuse large B-cell lymphoma.