PLAU and neoplasm: FOXM1 has been demonstrated to crosstalk with the TGF-β and Wnt pathways and its expression is correlated with MMP-2, MMP-9, VEGF, and urokinase-type plasminogen activator (uPA), and hence, FOXM1 can modulate angiogenesis, migration, and proliferation of tumor cells [169,170].