NFKBIA and myocardial infarction: This conclusion was confirmed by increased NF-κB nuclear translocation and promoted phosphorylation of IκB-α after treatment with APG in both MI/RI rats and OGD/R-stimulated neonatal rat cardiomyocytes, indicating that APG plays a substantial role in protecting the heart from MI/RI through NF-κB signalling pathway.